My work is focused on major mosquito vectors of disease. In particular, the rapid evolution and spread of resistance associated variants is a major focus. I am interested in investigating the underlying genetic mechanisms behind the regulation of resistance-associated genes, such as the involvement of non-coding RNAs. I am also interested in studying gene flow between populations of Anopheles mosquitoes, and how that may impact control programmes.
In 2017, I completed an MSc in Molecular Biology of Parasites and Disease Vectors at the Liverpool School of Tropical Medicine, in which I investigated mechanisms of resistance to the volatile pyrethroid, transfluthrin, under the supervision of Dr. David Weetman and Dr. Mark Paine. I soon re-joined the school as a molecular biology research technician, in which I continued to work in the field of insecticide resistance with Professor Hilary Ranson.
In the course of my PhD, I intend to apply machine learning algorithms to the Anopheles 1000 genomes data, as well as developing robust CRISPR-Cas based methodologies to investigate the role of specific variants in conferring resistance to insecticides.